NFKappaB-p65 (Acetyl Lys218) Polyclonal Antibody, 50ul Vessels subcellular location:Lacks the PDZ domain

subcellular location:Lacks the PDZ domain

Also involved in modulation of transcription

and plays an important role in transcriptional regulation

indicating that accessory factors may facilitate access to DNA

SFPQ may be involved in homologous DNA pairing

NFKappaB-p65 (Acetyl Lys218) Polyclonal Antibody, 50ul Vessels subcellular location:Lacks the PDZ domainNF kappa B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF kappa B moves to the nucleus and activates transcription of specific genes. NF kappa B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF kappa B is NFKB1 complexed with the product of this gene, RELA. Four