RUNX3 Polyclonal Antibody, 50ul[BT-AP08063] Thermal Control The encoded protein may interact

The encoded protein may interact with other cell cycle regulators

The protein encoded by this gene is a GTPase and member of the RAS-like GTP-binding protein family

such as SENP7

guanine nucleotide exchange factors (GEFs)

Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons

RUNX3 Polyclonal Antibody, 50ul[BT-AP08063] Thermal Control The encoded protein may interactRUNX3 encodes a member of the runt domain containing family of transcription factors. A heterodimer of this Runt related transcription factor 3 and a beta subunit forms a complex that binds to the core DNA sequence 5' PYGPYGGT 3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or