SMAD7 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos CALD1 encodes a calmodulin- and

CALD1 encodes a calmodulin- and actin-binding protein (caldesmon 1) that plays an essential role in the regulation of smooth muscle and nonmuscle contraction

The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells

which is several orders of magnitude faster than conventional molecular motor proteins

Transcripts of this gene have been reported in specimens of human testis

This protein exhibits mitogenic activity for keratinizing epidermal cells

SMAD7 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos CALD1 encodes a calmodulin- andThe protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF beta receptor type 1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding