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PTH/PTHrP-R Polyclonal Antibody, 100ul Bottles Alternative splicing generates several transcript

SKU: 70440470207

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PTH/PTHrP-R Polyclonal Antibody, 100ul Bottles Alternative splicing generates several transcriptThe protein encoded by PTH1R (parathyroid hormone 1 receptor) is a member of the G protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal

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Description

Alternative splicing generates several transcript variants

Similar to STAM| this protein acts downstream of JAK kinases| and is phosphorylated in response to cytokine stimulation

When bound to KRT17

and a MAM domain| which is believed to have an adhesive function

The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes

PTH/PTHrP-R Polyclonal Antibody, 100ul Bottles Alternative splicing generates several transcriptThe protein encoded by PTH1R (parathyroid hormone 1 receptor) is a member of the G protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal

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