Desmin Monoclonal Antibody(1B12), 50ul Antibodies intracellular N and C termini

intracellular N and C termini

The protein encoded by this gene has similarity to a mouse protein which suggests a role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum

PTM:Phosphorylated on Ser-13 in mitosis

resulting in the conversion of lysine to alpha-aminoadipic semialdehyde

function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation

Desmin Monoclonal Antibody(1B12), 50ul Antibodies intracellular N and C terminiThis gene encodes a muscle specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.