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HLAE Polyclonal Antibody, 50ul Sampling Tubes |tissue specificity:Expressed at low levels

SKU: 71806238549

4.9
USD162.00 USD212.00

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HLAE Polyclonal Antibody, 50ul Sampling Tubes |tissue specificity:Expressed at low levelsHLA E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. HLA E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1

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Description

|tissue specificity:Expressed at low levels in several tissues| including brain| kidney| lung| prostate| testis| spinal cord| adrenal gland| and trachea

whereby it binds complement C8 and/or C9 during the assembly of this complex

It is widely distributed in peripheral organs| such as liver and kidney| and is also present in low amounts in the central nervous system

and the gene is clustered with genes KCNA1 and KCNA5 on chromosome 12

This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase

HLAE Polyclonal Antibody, 50ul Sampling Tubes |tissue specificity:Expressed at low levelsHLA E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. HLA E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1

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