DEN1A Rabbit Polyclonal Antibody, 100ul Antibodies Among its related pathways are

Among its related pathways are Signaling by GPCR and cAMP signaling pathway

A pseudogene of this gene is found on chromosome 16

increased susceptibility to rheumatoid arthritis

This secreted protein undergoes a complex proteolytic maturation

This gene family has multiple members on both X and Y chromosomes| and all are expressed exclusively in male germ cells

DEN1A Rabbit Polyclonal Antibody, 100ul Antibodies Among its related pathways areClathrin (see MIM 118955) mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family such as DENND1A function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein 2 (AP2; see MIM 601024). Thus connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson 2010