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Neurotrimin Polyclonal Antibody, 50ul sgRNA Library Construction |enzyme regulation:Contains an N-terminal autoinhibitory

SKU: 77265329907

4.3
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Neurotrimin Polyclonal Antibody, 50ul sgRNA Library Construction |enzyme regulation:Contains an N-terminal autoinhibitoryNTM encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain containing glycosylphosphatidylinositol (GPI) anchored cell adhesion molecules. The encoded protein may promote neurite outgrowth and adhesion via a homophilic mechanism. Neurotrimin is closely linked to a related family member, opioid binding protein cell adhesion molecule like (OPCML), on chromosome 11. Multiple transcript variants encoding different isoforms

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Description

|enzyme regulation:Contains an N-terminal autoinhibitory domain

Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma

An important paralog of this gene is GPRIN3

Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome

Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin

Neurotrimin Polyclonal Antibody, 50ul sgRNA Library Construction |enzyme regulation:Contains an N-terminal autoinhibitoryNTM encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain containing glycosylphosphatidylinositol (GPI) anchored cell adhesion molecules. The encoded protein may promote neurite outgrowth and adhesion via a homophilic mechanism. Neurotrimin is closely linked to a related family member, opioid binding protein cell adhesion molecule like (OPCML), on chromosome 11. Multiple transcript variants encoding different isoforms

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