BRCA1 Polyclonal Antibody, 100ul[BT-AP00966] Isothermal Amplification The encoded protein shares significant

The encoded protein shares significant similarity with Arabidopsis FUS6

possessing a unique N-terminal membrane-associated domain and the stathmin-like domain at the C terminus

and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells

May play a role in JNK activation

The protein encoded by this gene has homologs that have been identified in mouse| macaque| etc organisms

BRCA1 Polyclonal Antibody, 100ul[BT-AP00966] Isothermal Amplification The encoded protein shares significantBRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated) combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal