AES Polyclonal Antibody, 20ul Cell Biology Mutations in this gene result

Mutations in this gene result in alpha-2-plasmin inhibitor deficiency| which is characterized by severe hemorrhagic diathesis

Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity

The protein encoded by this gene is a secreted

Alternatively spliced transcripts encoding the same protein have been identified

The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4

AES Polyclonal Antibody, 20ul Cell Biology Mutations in this gene resultThe protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho a protein involved in neurogenesis during embryonic development. The encoded protein which belongs to the groucho TLE family of proteins can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms