HSF1 Polyclonal Antibody, 100ul[BT-AP04230] Fluorescent Staining Members of this gene family

Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains

The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the Catalytic activity is acquired

Accumulation of EXPAND1/MUM1 at damaged DNA sites is thought to modify the structure of the chromatin and allow access to other DNA repair factors

The encoded protein is processed from a precursor

and modulation of adhesion molecule expression

HSF1 Polyclonal Antibody, 100ul[BT-AP04230] Fluorescent Staining Members of this gene familyThe product of HSF1 is a heat shock transcription factor. Transcription of heat shock genes is rapidly induced after temperature stress. Hsp90, by itself and or associated with multichaperone complexes, is a major repressor of HSF1.