Raf-1 Polyclonal Antibody, 100ul[BT-AP13537] Recombinant Protein Expression and also dominant nonimmune chronic

and also dominant nonimmune chronic idiopathic neutropenia of adults

with some of the isoforms being membrane-bound and others being soluble

Polymorphisms in this gene may be associated with increased risk of arrhythmias and sudden cardiac death

and hence neuronal excitability

The exact function of the encoded protein is not known

Raf-1 Polyclonal Antibody, 100ul[BT-AP13537] Recombinant Protein Expression and also dominant nonimmune chronicThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.