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PEA-15 Polyclonal Antibody, 50ul[BT-AP07045] Lysosome Our adenoviral packaging system can

SKU: 8629849577

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PEA-15 Polyclonal Antibody, 50ul[BT-AP07045] Lysosome Our adenoviral packaging system canPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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Description

Our adenoviral packaging system can accommodate large gene fragments and ensures high-level expression of target genes

An alternatively spliced transcript variant of this gene has been reported| however| its full length nature is not known

This family of genes encodes multi-pass membrane proteins that are similar to both the chemokine and the transmembrane 4 superfamilies of signaling molecules

with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane

Increasing evidence also suggests that CNT2 may have a role in energy metabolism because activation of CNT2 relies on the opening of ATP-sensitive K+ channels

PEA-15 Polyclonal Antibody, 50ul[BT-AP07045] Lysosome Our adenoviral packaging system canPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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