Dok-3 Polyclonal Antibody, 50ul General Lab Use Mutations in this gene are

Mutations in this gene are associated with megalencep

374 amino acids with all 11 kinase subdomains

and instead have a conserved lysine in subdomain I

Knockdown studies in zebrafish suggest that this gene is essential for normal inner ear function

While the biological activities of these receptors have yet to be determined

Dok-3 Polyclonal Antibody, 50ul General Lab Use Mutations in this gene areDok 1, Dok 2 and Dok 3 are members of a class of "docking" proteins which contain multiple tyrosine residues and putative SH2 binding sites. Dok 1 associates with the Ras GTPase activating protein (Ras GAP) upon tyrosine phosphorylation. Dok 2 (also designated p56 Dok) has also been identified as a potential mediator of the effects of p210 Bcr Abl. Dok 3 is an adapter involved in the recruitment of inhibitory molecules and is highly expressed in B