ALK Polyclonal Antibody, 50ul[BT-AP00371] Culture Plate Inserts More importantly| the C-terminal product

More importantly| the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product| restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the developing embryo

RANBP6 (RAN Binding Protein 6) is a Protein Coding gene

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Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2

The C-terminal fragment localizes to the cytoplasm while the N-terminal fragment localizes exclusively to the nucleus

ALK Polyclonal Antibody, 50ul[BT-AP00371] Culture Plate Inserts More importantly| the C-terminal productALK encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. ALK tyrosine kinase receptor comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or