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IFI-16 Polyclonal Antibody, 50ul Pipette Controller A chromosomal translocation and gene

SKU: 87664692149

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SEK142.00 SEK190.00

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IFI-16 Polyclonal Antibody, 50ul Pipette Controller A chromosomal translocation and geneIFI16 encodes a member of the HIN 200 (hematopoietic interferon inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma 1. It modulates p53 function, and inhibits cell growth in the Ras Raf signaling pathway.

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Description

A chromosomal translocation and gene fusion between this gene and zinc finger| MIZ-type containing 1 (Gene ID: 57178) may underlie intellectual disability and neuropsychiatric problems in a human patient

or sudden infant death syndrome

Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region

P2RY8 is moderately expressed in undifferentiated HL60 cells

get precise and efficient restriction digestion for your DNA research

IFI-16 Polyclonal Antibody, 50ul Pipette Controller A chromosomal translocation and geneIFI16 encodes a member of the HIN 200 (hematopoietic interferon inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma 1. It modulates p53 function, and inhibits cell growth in the Ras Raf signaling pathway.

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