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NF-YC Polyclonal Antibody, 100ul Sealing Film It is an intergral membrane

SKU: 87683907403

4.9
PLN123.75 PLN159.75

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NF-YC Polyclonal Antibody, 100ul Sealing Film It is an intergral membraneNFYC encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone like motif. Multiple transcript variants

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Description

It is an intergral membrane protein that is highly expressed in fetus

Knockout of this gene in mouse results in early embryonic lethality with phenotypes that include neurectoderm expansion

and is therefore a potential candidate gene for this disorder

It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation

which causes progressive bone overgrowth

NF-YC Polyclonal Antibody, 100ul Sealing Film It is an intergral membraneNFYC encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone like motif. Multiple transcript variants

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