PLXB1 Polyclonal Antibody, 100ul Electrophoresis & Labeling Several alternatively spliced transcript variants

Several alternatively spliced transcript variants of this gene have been described| but their biological validity has not been determined

This cyclin binds both CDK2 and CDC2 kinases

Alterations in levels of the encoded protein may be associated with many diseases

suggesting that it may also play an important role in cells undergoing rapid cell division

The protein (ataxin 2) encoded by ATXN2 has two globular domains near the N-terminus

PLXB1 Polyclonal Antibody, 100ul Electrophoresis & Labeling Several alternatively spliced transcript variantsdisease: Overexpressed and constitutively tyrosine phosphorylated in colon, liver, pancreas and gastric carcinoma cell lines. Overexpression increases MET activation and promotes invasive growth.,Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.,PTM: Phosphorylated on tyrosine residues by ERBB2 and MET upon SEMA4D binding.,PTM: