Shc Polyclonal Antibody, 50ul[BT-AP08289] Cell Proliferation There are a number of

There are a number of related genes present on chromosomes 20 and 22| and putative pseudogenes for this gene on chromosomes 2| 13| and 22

a brain-specific extracellular matrix protein

ISO 13485 (medical device quality management system) and ISO 9001 certified

Rho family small GTPases

MIM 602465)/SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade (see MAPK1

Shc Polyclonal Antibody, 50ul[BT-AP08289] Cell Proliferation There are a number ofSHC1 (SHC adaptor protein 1) encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in