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Aldolase B Polyclonal Antibody, 50ul Peptide Synthesis Members of the PAX family

SKU: 89284080411

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Aldolase B Polyclonal Antibody, 50ul Peptide Synthesis Members of the PAX familyFructose 1,6 bisphosphate aldolase (EC 4. 1. 2. 13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose 1,6 bisphosphate to glyceraldehyde 3 phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping'

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Description

Members of the PAX family typically contain a paired box domain and a paired-type homeodomain

which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II

There are 3 distinct domains of this factor: extracellular

while others have lost or perhaps never acquired this inhibitory activity

Mutations in this gene cause nephronophthisis (NPHP)| an autosomal recessive kidney disease characterized by tubular basement membrane disruption| interstitial lymphohistiocytic cell infiltration| and development of cysts at the corticomedullary border of the kidneys

Aldolase B Polyclonal Antibody, 50ul Peptide Synthesis Members of the PAX familyFructose 1,6 bisphosphate aldolase (EC 4. 1. 2. 13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose 1,6 bisphosphate to glyceraldehyde 3 phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping'

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