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NEK1 Polyclonal Antibody, 50ul Yeast Expression The exact function of the

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NEK1 Polyclonal Antibody, 50ul Yeast Expression The exact function of theThe protein encoded by this gene is a serine threonine kinase involved in cell cycle regulation. The encoded protein is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. Defects in this gene are a cause of polycystic kidney disease (PKD). Several transcript variants encoding different isoforms have been found for this gene.

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Description

The exact function of the encoded protein is not known

like all members of the GPCR superfamily

are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin

This gene is located adjacent to the imprinted domain in the Prader-Willi syndrome deletion region of chromosome 15

It is present with an interindividual variation in copy number and between 20 to 103 copies can be found both on chromosome 4 and chromosome 8

NEK1 Polyclonal Antibody, 50ul Yeast Expression The exact function of theThe protein encoded by this gene is a serine threonine kinase involved in cell cycle regulation. The encoded protein is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. Defects in this gene are a cause of polycystic kidney disease (PKD). Several transcript variants encoding different isoforms have been found for this gene.

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