PCD17 Rabbit Polyclonal Antibody, 20ul Transporters This enzyme is localized to

This enzyme is localized to the mitochondria and may play a role in programmed cell death

The gene product interacts with certain inflammatory response factors| and polymorphisms of this gene may be involved in the pathogenesis of Alzheimer's disease

SUBCELLULAR LOCATION: Cell membrane

Also| it is thought that the presenilins are involved in the cleavage of the Notch receptor such that| they either directly regulate gamma-secretase activity| or themselves act are protease enzymes

Inducible expression of IRF7 is largely restricted to lymphoid tissue

PCD17 Rabbit Polyclonal Antibody, 20ul Transporters This enzyme is localized toThis gene belongs to the protocadherin gene family a subfamily of the cadherin superfamily. The encoded protein contains six extracellular cadherin domains a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein may play a role in the establishment and function of specific cell cell connections in the brain.