PBF Polyclonal Antibody, 50ul Drug Development and Evaluation This gene is expressed mainly

This gene is expressed mainly in testis with weak expression in the brain

Pseudogenes exist on chromosomes 7 and 8

The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity

and polymorphisms that alter expression of ERCC1 may play a role in carcinogenesis

The epitopes that elicit these autoantibodies are localized largely to the non-collagenous C-terminal domain of the protein

PBF Polyclonal Antibody, 50ul Drug Development and Evaluation This gene is expressed mainlyPTTG1IP (pituitary tumor transforming 1 interacting protein) encodes a single pass type I integral membrane protein, which binds to pituitary tumor transforming 1 protein (PTTG1), and facilitates translocation of PTTG1 into the nucleus. Coexpression of this protein and PTTG1 induces transcriptional activation of basic fibroblast growth factor. Alternatively spliced transcript variants have been found for PTTG1IP.