RHPN2 Polyclonal Antibody, 100ul Bottle-Top Dispenser Two modes of SLAM signaling

Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates

Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described

It gives rise to maternally| paternally| and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons

E2 (ubiquitin conjugating)

PDZ domain and a C-terminal PDZ-binding motif

RHPN2 Polyclonal Antibody, 100ul Bottle-Top Dispenser Two modes of SLAM signalingThis gene encodes a member of the rhophilin family of Ras homologous (Rho) GTPase binding proteins. The encoded protein binds both GTP and GDP bound RhoA and GTP bound RhoB and may be involved in the organization of the actin cytoskeleton.