Dynein LC 1 Polyclonal Antibody, 50ul NGS Oligos An individual with autism and

An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene

generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors

Members of this family are regulated by the GTPase Ran to mediate transport of cargo across the nuclear envelope

and play a role in spindle formation during mitosis

Substrates of this protease include the proteins cadherin 2 and matrix metallopeptidase 2 (also known as 72 kDa type IV collagenase)

Dynein LC 1 Polyclonal Antibody, 50ul NGS Oligos An individual with autism andDNAL1 encodes an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP dependent manner. Dynein axonemal light chain 1 is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella. Alternate splicing results in multiple transcript variants.