Tuberin(Phospho Thr1462) Polyclonal Antibody, 50ul Plasma An important paralog of this

An important paralog of this gene is GK

The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex

The protein encoded by BAX belongs to the BCL2 protein family

and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins

Gene Ontology (GO) annotations related to this gene include death receptor binding

Tuberin(Phospho Thr1462) Polyclonal Antibody, 50ul Plasma An important paralog of thisMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.