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Sal003 55283 InChi: InChI=1S/C17H14O3/c18-15(11-9-13-5-1-3-7-16(13)19)12-10-14-6-2-4-8-17(14)20/h1-12

Sal003 55283 InChi: InChI=1S/C17H14O3/c18-15(11-9-13-5-1-3-7-16(13)19)12-10-14-6-2-4-8-17(14)20/h1-12

Name: Sal003 55283 InChi: InChI=1S/C17H14O3/c18-15(11-9-13-5-1-3-7-16(13)19)12-10-14-6-2-4-8-17(14)20/h1-12
Brand: athenaprestige.com
SKU: 15545483751
Price: 85.00 USD
Availability: InStock
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SKU: 15545483751

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Sal003 55283 InChi: InChI=1S/C17H14O3/c18-15(11-9-13-5-1-3-7-16(13)19)12-10-14-6-2-4-8-17(14)20/h1-12SAL 003 is a cell permeable inhibitor of eIF2 dephosphorylation. SAL003 is an Analog of salubrinal (Cat. No. 2347) with improved aqueous solubility. Sal003mediated upregulation of eIF2 phosphorylation suppressed cisplatininduced p53 activation. Furthermore, reduction of eIF2 phosphorylation by PERK knockdown enhanced cisplatin induced p53 activation and apoptosis. Product information CAS Number: 1164470 53 4 Molecular Weight: 463. 21 Formula:

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Description

InChi: InChI=1S/C17H14O3/c18-15(11-9-13-5-1-3-7-16(13)19)12-10-14-6-2-4-8-17(14)20/h1-12

PubMed PMID: 25296383

Steegmaier M

It is highly selective for the H1 receptor and does not cross the blood-brain-barrier

liver damage

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