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Olcegepant - CAS# 204697-65-4 Catalog No.:M10814-10 which may have potential application

Olcegepant - CAS# 204697-65-4 Catalog No.:M10814-10 which may have potential application

Name: Olcegepant - CAS# 204697-65-4 Catalog No.:M10814-10 which may have potential application
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Olcegepant - CAS# 204697-65-4 Catalog No.:M10814-10 which may have potential applicationOlcegepant, also known as BIBN 4096 or BIBN 4096BS is is the first potent and selective non peptide antagonist of the calcitonin gene related peptide 1 (CGRP1) receptor, a key modulator in neurogenic inflammatory pain. In preclinical studies, olcegepant attenuated arterial dilation induced by CGRP or electrical stimulation. In a phase II clinical trial, olcegepant reduced the severity of headache in 60% of migraine sufferers and met secondary

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which may have potential application in treating anemia of chronic disease

InChi: InChI=1S/C20H21N3O2/c1-12-6-5-7-14(21-12)18-17(22-19(23-18)20(2

Smiles: CCOC(=O)C1=CN=CN1[C@H](C)C1C=CC=CC=1

CAS Number: 480449-71-6

Epub 2008 Feb 6

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