MIM1 oitin sulfate Ingenol Mebutate (PEP005) activates PKCδ

Ingenol Mebutate (PEP005) activates PKCδ and inhibits PKCα

Tumor-promoting activity of staurosporine

6-diethylphenyl)-3-(4-(4-methylpiperazin-1-yl)benzamido)pyrrolo[3

CAS Number: 5053-08-7

Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85

MIM1 oitin sulfate Ingenol Mebutate (PEP005) activates PKCδMIM1 is an inhibitor of Mcl 1, an antiapoptotic Bcl 2 family protein that selectively engages the canonical groove of Mcl 1, inhibiting its ability to bind BH3 domains. MIM1 induces caspase 3 7 activation and cell death in Mcl 1 dependent leukemia cells. Product information CAS Number: 509102 00 5 Molecular Weight: 347. 43 Formula: C17H21N3O3S Synonym: MIM 1 MIM 1 Inhibitor of Mcl 1 Chemical Name: 4 [(1E) {[2 (cyclohexylimino) 4 methyl 2,3 dihydro 1,3