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Amlexanox - CAS# 68302-57-8 Size:2 mg solid Chemical Name: (2Z)-but-2-enedioic acid

SKU: 36736010342

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Amlexanox - CAS# 68302-57-8 Size:2 mg solid Chemical Name: (2Z)-but-2-enedioic acidAmlexanox, also known as AA 673 and CHX 3673, is an anti inflammatory antiallergic immunomodulator used to treat recurrent aphthous ulcers (canker sores), and (in Japan) several inflammatory conditions. Amlexanox inhibits the synthesis and release of inflammatory mediators, including leukotrienes and histamine, from mast cells, neutrophils, and mononuclear cells. Amlexanox also acts as a leukotriene D4 antagonist and a phosphodiesterase inhibitor.

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Description

Chemical Name: (2Z)-but-2-enedioic acid

Smiles: O=C1CC2=C(NC3=CC=C(Br)C=C32)C2=CC=CC=C2N1

BMS-983970 is a pan-Notch inhibitor

KU-60019 at 3 μM significantly inhibits migration and invasion of human glioma U87 cells by >70% and ~60%

PubMed PMID: 25450629

Amlexanox - CAS# 68302-57-8 Size:2 mg solid Chemical Name: (2Z)-but-2-enedioic acidAmlexanox, also known as AA 673 and CHX 3673, is an anti inflammatory antiallergic immunomodulator used to treat recurrent aphthous ulcers (canker sores), and (in Japan) several inflammatory conditions. Amlexanox inhibits the synthesis and release of inflammatory mediators, including leukotrienes and histamine, from mast cells, neutrophils, and mononuclear cells. Amlexanox also acts as a leukotriene D4 antagonist and a phosphodiesterase inhibitor.

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