Pazopanib Hydrochloride Catalog No.:M10929-2 CAS Number: 204519-66-4

CAS Number: 204519-66-4

mice) shows improved efficacy (regression) in a 92

InChi: InChI=1S/C20H14ClN3O/c21-16-7-6-15(12-17(16)25)19-18(13-8-10-22-11-9-13)23-20(24-19)14-4-2-1-3-5-14/h1-12

Hammond LA

translation and DNA synthesis in sensitive cells (HCC4017 and H292 cells) but not insensitive cells (HBEC30KT cells and HCC44 cells)

Pazopanib Hydrochloride Catalog No.:M10929-2 CAS Number: 204519-66-4Pazopanib HCl (GW786034 HCl) is a novel multi target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c Kit and c Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell free assays, respectively. Pazopanib induces autophagic Type II cell death. Product information CAS Number: 635702 64 6 Molecular Weight: 473. 98 Formula: C21H24ClN7O2S Chemical Name: 5 ({4 [(2,3 dimethyl 2H indazol 6 yl)(methyl)amino]pyrimidin 2 yl}amino) 2