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DDR1-IN-1 - CAS# 1449685-96-4 size:10mg solid Formula: C24H20N4O

DDR1-IN-1 - CAS# 1449685-96-4 size:10mg solid Formula: C24H20N4O

Name: DDR1-IN-1 - CAS# 1449685-96-4 size:10mg solid Formula: C24H20N4O
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SKU: 41968331813
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SKU: 41968331813

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DDR1-IN-1 - CAS# 1449685-96-4 size:10mg solid Formula: C24H20N4ODDR1 IN 1, CAS No. 1449685 96 4, is a potent and selective DDR1 inhibitor with IC50 of 105 nM, about 3 fold selectivity over DDR2. DDR1 IN 1 binds to DDR1 in the 'DFG out' conformation and inhibits DDR1 autophosphorylation in cells at submicromolar concentrations with good selectivity as assessed against a panel of 451 kinases measured. DDR1 IN 1 provides a useful pharmacological probe for DDR1 dependent signal transduction. The DDR1 receptor tyrosine

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Description

Formula: C24H20N4O

894002-50-7

KGN also shows chondro-protective effects in vitro

is a substance found in the sap of the plant Euphorbia peplus and an inducer of cell death

SCHEMBL15506294

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