SB-334867 (base) - an orexin antagonist. CAS# 792173-99-0 size:2mg solid Inhibitors of Hedgehog acyltransferase block

Inhibitors of Hedgehog acyltransferase block Sonic Hedgehog signaling

which is the first selective and potent inhibitor of the H3K27 histone demethylases UTX and JMJD3

Chemical Name: 2-(4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl)-1-(1H-1

2016 Feb 12

and other clinically important ABL kinase domain mutants (IC50: 0

SB-334867 (base) - an orexin antagonist. CAS# 792173-99-0 size:2mg solid Inhibitors of Hedgehog acyltransferase blockSB 334867, an orexin antagonist, CAS No. 792173 99 0, is an orexin antagonist. SB 334867 was the first non peptide antagonist developed that is selective for the orexin receptor subtype OX1, with around 50x selectivity for OX1 over OX2 receptors. It has been shown to produce sedative and anorectic effects in animals, and has been useful in characterising the orexinergic regulation of brain systems involved with appetite and sleep, as well as other