LY341495 aplatin CAS Number: 82586-52-5

CAS Number: 82586-52-5

highly selective 5-HT(1F) receptor agonist (K1=2

Although Nutlin-3 also inhibits the growth and viability of human skin (1043SK) and mouse embryo (NIH/3T3) with IC50 of 2

Solubility: DMSO : 100 mg/mL (189

HCT-116 and MiaPaca cells

LY341495 aplatin CAS Number: 82586-52-5LY 341495 is a potent and selective orthosteric antagonist for the group II metabotropic glutamate receptors (mGluR2 3). Ki IC50 values of LY 341495 are 2. 3, 1. 3, 173, 990, 6800, 8200 and 22000 nM for human mGlu2, mGlu3, mGlu8 , mGlu7a, mGlu1a, mGlu5a and mGlu4a receptors respectively. It is used in scientific research in several different areas, showing antidepressant effects in animal models, increasing the behavioural effects of hallucinogenic