LXR-623 5363 InChiKey: NCJPFQPEVDHJAZ-UHFFFAOYSA-N

InChiKey: NCJPFQPEVDHJAZ-UHFFFAOYSA-N

after which the tumors are left to grow out

is a second-generation

082 nM (in membrane-assay/in cell-basedγ-secretase assays)) and also inhibits Notch clevage (IC50= 0

Chemical Name: hexasodium (1R

LXR-623 5363 InChiKey: NCJPFQPEVDHJAZ-UHFFFAOYSA-NLXR623, also known as WAY 252623, is a highly selective and orally bioavailable synthetic modulator of LXR, which demonstrated efficacy for reducing lesion progression in the murine LDLR( ) atherosclerosis model with no associated increase in hepatic lipogenesis either in this model or Syrian hamsters. In nonhuman primates with normal lipid levels, WAY 252623 significantly reduced total (50 55%) and LDL cholesterol (LDLc) (70 77%) in a time and dose