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CAL-130 Hydrochloride - CAS# 1431697-78-7 ifabutin LiverTox: Clinical and Research Information

CAL-130 Hydrochloride - CAS# 1431697-78-7 ifabutin LiverTox: Clinical and Research Information

Name: CAL-130 Hydrochloride - CAS# 1431697-78-7 ifabutin LiverTox: Clinical and Research Information
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CAL-130 Hydrochloride - CAS# 1431697-78-7 ifabutin LiverTox: Clinical and Research InformationCAL 130 is a potent and selective PI3K gamma and delta inhibitor with potential anticancer activity. Constitutive phosphoinositide 3 kinase (PI3K) Akt activation is common in T cell acute lymphoblastic leukemia (T ALL). Although four distinct class I PI3K isoforms (, , , ) could participate in T ALL pathogenesis, none has been implicated in this process. In the absence of PTEN phosphatase tumor suppressor function, PI3K or PI3K alone can support

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Description

LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]

Gardell SJ

CAS Number: 58-32-2

Fenretinide inhibits OVCAR-5 cell proliferation and viability at concentrations higher than 1 microM

Formula: C25H43NO18

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