AEE788 igomycin A Pirfenidone

Pirfenidone

While the plasma levels of PD 153035 falls below 1 μM by 3 hours

Formula: C34H50N4O9S

HG-10-102-01 is the first compound reported to be capable of inhibiting Ser910 and Ser935 phosphorylation in mouse brain following intraperitoneal delivery of doses as low as 50 mg/kg

InChi: InChI=1S/C6H13NO3S/c7-5(6(9)10)4-11-3-1-2-8/h5

AEE788 igomycin A PirfenidoneAEE 788 is an orally bioavailable multiple receptor tyrosine kinase inhibitor. AEE788 inhibits phosphorylation of the tyrosine kinases of epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2), and vascular endothelial growth factor receptor 2 (VEGF2), resulting in receptor inhibition, the inhibition of cellular proliferation, and induction of tumor cell and tumor associated endothelial cell apoptosis. Check for