Apilimod dimesylate - CAS# 870087-36-8 077 5-10 µM in vitro and

5-10 µM in vitro and cellular assays

CAS Number: 1375466-18-4

Formula: C25H31N3O5S2

InChi: InChI=1S/C30H47N5O2/c1-22(2)35-17-12-24(13-18-35)31-30-25-20-27(36-3)28(37-19-9-16-34-14-7-8-15-34)21-26(25)32-29(33-30)23-10-5-4-6-11-23/h20-24H

a highly selective inhibitor of heat shock protein 90α and β

Apilimod dimesylate - CAS# 870087-36-8 077 5-10 µM in vitro andApilimod dimesylate, CAS No. 870087 36 8, also known as STA 5326, is a IL 12 IL 23 inhibitor. Apilimod inhibits IL 12 and IL 23 production cytokines that are involved in autoimmune diseases through the prevention of nuclear translocation of c Rel. Synta Pharmaceuticals Corp is developing apilimod for the potential treatment of Crohn's disease (CD) and other autoimmune diseases. Preclinical studies demonstrated the successful inhibition of IL 12 and IL